New Approaches in Medical Biology

This book explores the effects of omega-3 fatty acids on certain types of cancer, psoriasis and its treatment, comorbidities associated with psoriasis, and the role of ursolic acid in repairing nickel-induced kidney damage. Omega-3 fatty acids, particularly alpha-linolenic acid, have been shown to reduce cancer cell proliferation and possess anti-inflammatory and anti-proliferative properties, presenting promising prospects in cancer therapy. Psoriasis is a chronic immune-mediated skin disorder significantly reducing patient quality of life and is associated with numerous comorbidities. Treatment options range from topical therapies for mild cases to systemic drugs, biologics, and phototherapy for moderate to severe conditions. Comorbidities include psoriatic arthritis, cancer, depression, infections, kidney and cardiovascular diseases, and liver disorders. Ursolic acid demonstrates protective antioxidant effects by alleviating nickel-induced renal toxicity in rats and may serve as a potential therapeutic agent. Overall, the studies offer a comprehensive view of disease mechanisms, nutritional impacts, inflammation, and therapeutic strategies in medical biology.